A mouse model of recrudescence of Toxoplasma gondii infection

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A mouse model of recrudescence of Toxoplasma gondii infection.

Dexamethasone was given to mice infected with Toxoplasma gondii to provide a model of recrudescence of infection in immunocompromised patients and to permit investigation of the interaction between parasite and host.

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Proteomic Profiling of Mouse Liver following Acute Toxoplasma gondii Infection.

Toxoplasma gondii remains a global public health problem. However, its pathophysiology is still not-completely understood particularly the impact of infection on host liver metabolism. We performed iTRAQ-based proteomic analysis to evaluate early liver protein responses in BALB/c mice following infection with T. gondii PYS strain (genotype ToxoDB#9) infection. Our data revealed modification of ...

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Congenital Toxoplasma Gondii Infection

Pregnant women who acquire infection from Toxoplasma gondii usually remain asymptomatic, although they can still transmit the infection to their fetuses with severe consequences. Transmission of T. gondii to the fetus can result in serious health problems, including mental retardation, seizures, blindness, and death. Some health problems may not become apparent until the second or third decade ...

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Toxoplasma gondii Infection Induces Suppression in a Mouse Model of Allergic Airway Inflammation

Allergic asthma is an inflammatory disorder characterized by infiltration of the airway wall with inflammatory cells driven mostly by activation of Th2-lymphocytes, eosinophils and mast cells. There is a link between increased allergy and a reduction of some infections in Western countries. Epidemiological data also show that respiratory allergy is less frequent in people exposed to orofecal an...

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Toxoplasma gondii infection in slaughtered ewes in Khorramabad, west of Iran: A preliminary molecular study

BACKGROUND: The parasitic protozoa Toxoplasma gondii is widely prevalent in humans and warm-blooded animals. Humans are usually infected with T. gondii by ingesting oocysts shed by cats or by ingesting viable tissue cysts present in raw or undercooked meat. OBJECTIVES: This preliminary study was conducted to assess the frequency of Toxoplasma gondii infection in tissue samples of ewes slaughter...

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ژورنال

عنوان ژورنال: Journal of Medical Microbiology

سال: 1997

ISSN: 0022-2615,1473-5644

DOI: 10.1099/00222615-46-3-263